Research
Adherence
Dispensing rates for GLP-1 RAs are significantly lower for obesity (AOM) indications compared to diabetes (ADM) indications, with a large gap in 60-day initiation rates.
Even if prescribed, GLP-1 RAs for weight loss are less likely to be filled than those for diabetes, largely due to insurance coverage issues. If you are prescribed an AOM GLP-1 RA, proactively check your insurance coverage and explore assistance programs to ensure you can access the medication.
ModerateQualifiesMEDIUM confidence
71.5% of first-time ADM prescriptions overall and 74.9% in September 2023 had a fill within 60 days. By comparison, 45.6% of first-time AOM prescriptions overall and 32.1% in September 2023 had a fill within 60 days.
Why this rating
Real-world observational data.
Source
Monitoring Report: GLP-1 RA Prescribing Trends - September 2024 Data
Samuel Gratzl et al. · medRxiv · 2024
DOI 10.1101/2024.01.18.24301500
preprint · n=1063200Cited 18×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- GLP-1 receptor agonists (GLP-1 RAs) are prescribed for Type 2 Diabetes (ADM) and obesity (AOM), with semaglutide being the most commonly prescribed agent overall.Moderate
- Dispensing rates for GLP-1 RAs are lower in patients aged 65+ compared to those aged 18-64, particularly for AOM indications.Moderate
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