Research
Adherence
Dispensing rates for GLP-1 RAs are lower in patients aged 65+ compared to those aged 18-64, particularly for AOM indications.
Older adults (65+) are less likely to fill GLP-1 RA prescriptions for weight loss compared to younger adults, largely due to Medicare not covering these medications. If you are 65 or older, discuss alternative coverage options or patient assistance programs with your healthcare provider.
ModerateQualifiesMEDIUM confidence
60-day AOM initiation rates for the 65+ population (23.6% in September 2023) are lower than AOM initiation rates for the population aged 18-64 (32.9% in September 2023).
Why this rating
Real-world observational data.
Source
Monitoring Report: GLP-1 RA Prescribing Trends - September 2024 Data
Samuel Gratzl et al. · medRxiv · 2024
DOI 10.1101/2024.01.18.24301500
preprint · n=1063200Cited 18×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- GLP-1 receptor agonists (GLP-1 RAs) are prescribed for Type 2 Diabetes (ADM) and obesity (AOM), with semaglutide being the most commonly prescribed agent overall.Moderate
- Dispensing rates for GLP-1 RAs are significantly lower for obesity (AOM) indications compared to diabetes (ADM) indications, with a large gap in 60-day initiation rates.Moderate
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →