Research
Energy balance
Exercise and weight loss are effective if done early and sufficiently.
Encouraging early intervention with exercise and weight loss can improve patient outcomes.
StrongSupportsmedium confidence
Exercise and weight loss are effective if done early and sufficiently.
Why this rating
The claim is supported by the Look AHEAD study, which is a large RCT.
Source
Exclusion of ‘nonRCT evidence’ in guidelines for chronic diseases – is it always appropriate? The Look AHEAD study
Richard Kones et al. · Current Medical Research and Opinion · 2014
DOI 10.1185/03007995.2014.925438
reviewCited 13×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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