Research
Molecular
GIPR activation influences energy balance and insulin sensitivity through mechanisms involving metabolic and thermogenic genes.
Understanding the molecular mechanisms of GIPR could inform strategies for improving insulin sensitivity.
StrongSupportsmedium confidence
The systemic insulin sensitization was accompanied by increased glucose disposal in brown adipose tissue, which was underlined by the recruitment of metabolic and thermogenic genes.
Why this rating
Based on the experimental design involving RNA sequencing.
Source
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Ellen C Furber et al. · Diabetes · 2023
otherCited 12×
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