Research
Energy balance
Nitro-oleic acid treatment does not alter body weight in Nrf2fl/fl and ANKO mice on both high fat diet (HFD) and low-fat diet (LFD).
NO2-OA may not affect body weight, suggesting its effects are more focused on metabolic parameters rather than weight loss.
StrongSupportsmedium confidence
NO2-OA treatment did not alter body weight between ANKO and littermate controls (Nrf2fl/fl) mice on both the HFD and low-fat diet (LFD).
Why this rating
Based on study design from abstract.
Source
Adipocyte-specific Nrf2 deletion negates nitro-oleic acid benefits on glucose tolerance in diet-induced obesity
Dionysios V. Chartoumpekis et al. · Nitric Oxide · 2024
DOI 10.1016/j.niox.2024.06.002
otherCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Nitro-oleic acid (NO2-OA) treatment improves glucose tolerance in high fat diet (HFD)-fed Nrf2fl/fl mice but does not improve glucose tolerance in adipocyte-specific Nrf2 knockout (ANKO) mice.Strong
- Adipocyte-specific deletion of Nrf2 negates the protective effects of nitro-oleic acid on glucose tolerance.Strong
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