Research
Neural
In patients with cardiovascular disease and diabetes mellitus, lower-extremity muscle strength is significantly associated with peak oxygen uptake (VO 2peak).
Practitioners should focus on improving lower-extremity muscle strength in patients with CVD and DM to enhance exercise capacity.
StrongSupportsmedium confidence
The IKES was significantly associated with VO 2peak in the DM group ( β = 0.83, P < .001).
Why this rating
Based on the cross-sectional study design with a substantial sample size.
Source
Impact of Lower-Extremity Muscle Strength on Exercise Capacity in Patients With Cardiovascular Disease and Diabetes Mellitus
Koya Takino et al. · Journal of Cardiopulmonary Rehabilitation and Prevention · 2025
DOI 10.1097/hcr.0000000000000962
cross-sectional · n=262
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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