Research
Neural
High stress is associated with a higher risk of coronary heart disease (CHD) and stroke compared to no stress.
High stress levels should be addressed in patients to mitigate risks of CHD and stroke.
StrongSupportsmedium confidence
High stress, but not low or moderate stress, was associated with CVD (HR, 1.22 [95% CI, 1.08-1.37]) and stroke (HR, 1.30 [95% CI, 1.09-1.56]) after adjustment.
Why this rating
Based on the large prospective cohort study design.
Source
Psychosocial Risk Factors and Cardiovascular Disease and Death in a Population-Based Cohort From 21 Low-, Middle-, and High-Income Countries
Ailiana Santosa et al. · JAMA Network Open · 2021
cohort · n=118706Cited 137×
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