Hormonal
Type 2 diabetic patients tend to experience a progressive decline in average body weight during the first 6 years after diagnosis, resulting in an average loss of 2.5 kg.
After being diagnosed with type 2 diabetes, it is common to lose an average of 2.5 kg over the next 6 years. This is often due to lifestyle changes and the physiological effects of the disease and treatment. This weight loss can be beneficial for your cardiovascular health.
During the first on average 5.7 years after diagnosis of type 2 diabetes, patients generally follow a course of declining average weight... During this time period patients lost on average 2.5 (6.5; -1.7) kg.
Why this rating
Large cohort, long follow-up, but observational.
Source
Weight Changes following the Diagnosis of Type 2 Diabetes: The Impact of Recent and Past Weight History before Diagnosis. Results from the Danish Diabetes Care in General Practice (DCGP) Study
Niels de Fine Olivarius et al. · PLoS ONE · 2015
DOI 10.1371/journal.pone.0122219
More from this paper
- In patients newly diagnosed with type 2 diabetes, recent weight gain (within one year prior to diagnosis) predicts subsequent weight loss after diagnosis, whereas long-term historical weight history (weight at age 20 or changes 10 years prior) does not predict post-diagnosis weight changes.Good
- Higher BMI at the time of diabetes diagnosis is a significant predictor of greater weight loss during the first 6 years following diagnosis.Good
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
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