Research
Mixed
Genetic variants (SNPs) associated with obesity, diabetes, and cardiovascular disease generally have small effect sizes and explain a small fraction of the overall variance in these conditions.
Understanding your genetics does not give you a free pass or a guaranteed outcome. Most genetic risks are small and can be managed. Focus on modifiable risk factors like BMI, blood pressure, and diet quality.
StrongQualifiesVERY_HIGH confidence
Since most identified gene variants have small effect sizes... carriers and non-carriers usually also have only slightly lower or higher risks than the average population... the majority of variants possess very low odd ratios ranging from 1.10 to 1.25 per allele.
Why this rating
Based on GWAS of hundreds of thousands of individuals.
Source
Genetics and Epigenetics in Personalized Nutrition: Evidence, Expectations, and Experiences
Christina Holzapfel et al. · Molecular Nutrition & Food Research · 2022
narrative_reviewCited 30×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →