Research

Mixed

The association between metabolic syndrome status changes and atrial fibrillation risk is significantly stronger in younger (20-39 years) and middle-aged (40-64 years) populations compared to the elderly (≥65 years).

If you are under 65, managing your metabolic health (weight, blood pressure, blood sugar) is even more critical for preventing atrial fibrillation than it is for those over 65. The risk of AF from metabolic syndrome is much higher in younger and middle-aged adults. Preventing metabolic syndrome early in life offers the greatest protection against AF.

GoodQualifiesHIGH confidence
The risk of AF was strongly correlated with MetS status changes in the young and middle- age groups (20– 39 years and 40– 64 years, respectively) than in the elderly group (≥65 years).
Seo‐Young Lee et al. · Journal of the American Heart Association · 2021

Why this rating

Large sample size allows for robust subgroup analysis, though observational nature remains.

Source

Association Between Change in Metabolic Syndrome Status and Risk of Incident Atrial Fibrillation: A Nationwide Population‐Based Study

Seo‐Young Lee et al. · Journal of the American Heart Association · 2021

DOI 10.1161/jaha.121.020901

cohort · n=7565531Cited 28×
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DOI resolved against Crossref · corpus check 2026-06-10

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