Research
Micronutrients & recovery
Digestive-system cancers (colorectal, pancreatic, esophageal) show the strongest inverse association with vitamin D status, with mortality reductions up to 45%.
For men, maintaining adequate Vitamin D levels may be particularly important for preventing digestive cancers. The study suggests a strong link between higher Vitamin D levels and lower mortality from colorectal, pancreatic, and esophageal cancers.
GoodSupportsHIGH confidence
For digestive system cancers, an increment of 25 nmol/L in the predicted 25(OH)D level was associated with a 43% reduction in incidence (RR = 0.57, 95% CI = 0.46 to 0.71) and a 45% reduction in mortality (RR = 0.55, 95% CI = 0.41 to 0.74).
Why this rating
Strong statistical significance for digestive cancer mortality, consistent across strata.
Source
Prospective Study of Predictors of Vitamin D Status and Cancer Incidence and Mortality in Men
Edward L. Giovannucci et al. · JNCI Journal of the National Cancer Institute · 2006
DOI 10.1093/jnci/djj101
cohort · n=47800Cited 1,047×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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