Research

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Cardiovascular-Kidney-Metabolic (CKM) syndrome is a systemic disorder characterized by pathophysiological interactions among metabolic risk factors, chronic kidney disease (CKD), and the cardiovascular system, leading to multiorgan dysfunction and high adverse outcome rates.

If you have high blood pressure, diabetes, or kidney issues, recognize that these conditions are linked and worsen each other. Managing one without addressing the others is less effective. Seek integrated care that looks at your heart, kidneys, and metabolic health together to prevent serious complications like heart failure or kidney failure.

StrongSupportsVERY_HIGH confidence
CKM syndrome is defined as a systemic disorder characterized by pathophysiological interactions among metabolic risk factors, CKD, and the cardiovascular system, leading to multiorgan dysfunction and a high rate of adverse cardiovascular outcomes.
Chiadi E. Ndumele et al. · Circulation · 2023

Why this rating

This is a scientific statement from the American Heart Association based on an extensive body of literature and crosswalk of major guidelines.

Source

A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association

Chiadi E. Ndumele et al. · Circulation · 2023

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