Energy balance
Intensive lifestyle interventions resulting in significant weight loss (approx. 8.6% at 1 year) improve glycaemic control, reduce cardiovascular risk factors, and induce remission of type 2 diabetes, although they have not been shown to reduce the rate of major cardiovascular events compared to standard care.
Focus on losing 7% of your body weight through diet and 150 minutes of moderate exercise weekly. This will significantly improve your blood sugar control and quality of life. While this may not statistically reduce heart attack rates in large groups, it is the most effective first-line treatment for managing Type 2 Diabetes.
Early results were promising, with analysis after 1 year showing a mean 8.6% weight loss with the intensive lifestyle intervention... The additional weight loss was associated with a significant reduction of glycosylated haemoglobin (HbA1c) levels and improvement in several other cardiovascular risk factors... complete or partial remission of T2DM... was seen in a small proportion of patients... major cardiovascular events had occurred in 403 patients in the intensive group compared with 418 in the control group (hazard ratio 0.95; 95% CI, 0.83–1.09, p = 0.51).
Why this rating
Based on large randomized controlled trials (Look AHEAD, UKPDS, Da Qing) and meta-analyses, though the primary cardiovascular endpoint was negative.
Source
The importance of weight management in type 2 diabetes mellitus
John Wilding · International Journal of Clinical Practice · 2014
DOI 10.1111/ijcp.12384
More from this paper
- Weight loss improves quality of life, mobility, physical function, and remission of obstructive sleep apnoea in T2DM patients, independent of cardiovascular event rates.Good
- Severe caloric restriction (Very Low Calorie Diet) can normalize beta-cell function and reverse Type 2 Diabetes, though it is not sustainable long-term for most patients.Moderate
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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