Research

Adherence

Intensive lifestyle intervention (ILI) preserves physical health-related quality of life (HRQoL) by slowing the age-related decline in physical functioning compared to standard diabetes support and education (DSE) in overweight/obese individuals with type 2 diabetes.

For those with type 2 diabetes, committing to a structured lifestyle program can help maintain physical function and quality of life over the long term, even if it doesn't drastically reverse age-related decline. The key benefit is slowing the rate of physical deterioration compared to those receiving standard care.

WeakQualifiesHIGH confidence
Although SF-36 PCS scores worsened over time in both groups, ILI participants reported better physical function than DSE throughout the first 8 years (all P values <0.01).
The Look AHEAD Research Group · Diabetes Care · 2014

Why this rating

Large-scale RCT with long-term follow-up and validated outcome measures (SF-36).

Source

Impact of Intensive Lifestyle Intervention on Depression and Health-Related Quality of Life in Type 2 Diabetes: The Look AHEAD Trial

The Look AHEAD Research Group · Diabetes Care · 2014

DOI 10.2337/dc13-1928

rct · n=5145Cited 216×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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