Research

Micronutrients & recovery

Supplementation with 25-hydroxyvitamin D3 (HyD) at 20 mg/day produces a significantly faster and higher increase in serum 25(OH)D levels compared to 800 IU/day of vitamin D3, resulting in superior improvements in lower extremity function and systolic blood pressure in postmenopausal women.

For postmenopausal women seeking to improve leg strength and lower blood pressure, 20 mg of 25-hydroxyvitamin D3 (HyD) taken daily is significantly more effective than 800 IU of standard Vitamin D3. HyD raises blood levels faster and higher, leading to better functional outcomes and a 5.7 mmHg drop in systolic blood pressure within 4 months. Consult a doctor before switching supplements.

ModerateSupportsMEDIUM confidence
Women on HyD compared with vitamin D3 had a 2.8-fold increased odds of maintained or improved lower extremity function (odds ratio [OR] = 2.79; 95% confidence interval [CI], 1.18–6.58), and a 5.7-mmHg decrease in systolic blood pressure (p = 0.0002).
Heike A. Bischoff‐Ferrari et al. · Journal of Bone and Mineral Research · 2011

Why this rating

Small sample size (n=20) but double-blind, randomized, and controlled design with multiple repeated measures.

Source

Oral supplementation with 25(OH)D3 versus vitamin D3: Effects on 25(OH)D levels, lower extremity function, blood pressure, and markers of innate immunity

Heike A. Bischoff‐Ferrari et al. · Journal of Bone and Mineral Research · 2011

rct · n=20Cited 194×
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