Research
Macro partitioning
An isocaloric ketogenic diet significantly lowers fasting triglycerides but raises fasting total, HDL, and LDL cholesterol compared to a baseline diet in men with overweight or obesity.
Switching to a ketogenic diet will likely lower your triglycerides but raise your total, LDL, and HDL cholesterol. This mixed effect means you should monitor your full lipid panel, not just triglycerides, to assess cardiovascular risk.
GoodQualifiesHIGH confidence
Fasting total and HDL cholesterol were significantly higher, and triglycerides were significantly lower during the KD.
Why this rating
Controlled inpatient study with objective biochemical measures.
Source
Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet
Michael Rosenbaum et al. · Obesity · 2019
DOI 10.1002/oby.22468
crossover · n=17Cited 104×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- An isocaloric ketogenic diet (5% carbohydrate, 80% fat) increases fasting inflammatory markers (CRP, adiponectin) and cholesterol (total, LDL, HDL) compared to a baseline diet (50% carbohydrate, 35% fat) in men with overweight or class I obesity.Good
- An isocaloric ketogenic diet decreases insulin-mediated antilipolysis (the ability of insulin to suppress fat breakdown) compared to a baseline diet, regardless of the meal consumed.Good
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