Polyphenols and unsaturated fats in the Mediterranean diet mitigate metabolic syndrome risk by suppressing proinflammatory cytokines and lipid peroxidation.

Olive oil, a fundamental element of the Mediterranean diet, contains polyphenols that are instrumental in mitigating the risk of metabolic syndrome by addressing factors such as visceral obesity, insulin resistance, hypertension, and lipid peroxidation. These polyphenols suppress the activation and expression of nuclear factor kappa B (NFKB)... thereby lowering the secretion of proinflammatory cytokines [55,56].