Hormonal

Metformin produces moderate weight loss (3-5% reduction) in adults with T2DM or obesity, primarily by lowering hunger and reducing calorie intake, and can prevent weight gain associated with antipsychotic medications.

Metformin is a cornerstone treatment for Type 2 Diabetes that also offers moderate weight loss benefits (typically 3-5% body weight reduction). It works by reducing appetite and calorie intake. It is particularly useful for patients who need to counteract weight gain caused by other medications, such as antipsychotics. While gastrointestinal side effects are common, they often subside, and the long-term weight and metabolic benefits are substantial.