Mixed
Femoral subcutaneous adipose tissue exhibits significantly higher in vivo preadipocyte and adipocyte formation rates compared to abdominal subcutaneous tissue in women.
Your body's fat distribution is biologically determined. In women, thigh fat (femoral) tends to have higher cell turnover and expansion capacity than belly fat (abdominal). This is why lower-body fat is often considered more metabolically protective. You cannot change this genetic predisposition, but understanding it explains why fat accumulates differently in different areas.
Importantly, our analyses identify higher in vivo preadipocyte and adipocyte formation in the scFEM depot compared with the scABD.
Why this rating
Small sample size (n=25), single sex (women), and specific population (overweight/obese), but uses robust in vivo kinetic labeling.
Source
Differences in In Vivo Cellular Kinetics in Abdominal and Femoral Subcutaneous Adipose Tissue in Women
Ursula White et al. · Diabetes · 2016
DOI 10.2337/db15-1617
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