Research

Mixed

High consumption of ultra-processed foods is associated with negative health outcomes including increased depression/anxiety, higher BMI/weight, and decreased HDL cholesterol, particularly in men consuming >5 servings/day.

Eating more than 5 servings of ultra-processed foods daily is linked to higher body weight, worse cholesterol (lower HDL in men), and higher rates of depression and anxiety in women. Reducing UPF intake below this threshold may help improve these health markers.

ModerateSupportsMEDIUM confidence
Women consuming >5 servings/day of UPFs reported more cases of depression and anxiety and higher weight and hip circumference. Meanwhile, men consuming >5 servings/day of UPFs had decreased levels of high-density lipoprotein (HDL) cholesterol and higher weight and BMI
Allison L. Brichacek et al. · Nutrients · 2024

Why this rating

Based on observational data with adjustments for confounders, but limited by cross-sectional design and small sample sizes in some subgroups.

Source

Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods

Allison L. Brichacek et al. · Nutrients · 2024

DOI 10.3390/nu16111738

narrative_reviewCited 41×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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