Research

Micronutrients & recovery

Lower plasma glycine levels are independently associated with higher BMI and male gender, suggesting glycine is a marker of favorable metabolic health and its reduction is a risk factor for metabolic syndrome.

Low glycine levels are linked to higher BMI and male gender, and may indicate higher metabolic risk. While this paper doesn't prescribe a glycine supplement dose, it highlights glycine as a key marker of metabolic health. Maintaining healthy body weight helps preserve glycine levels, which may support metabolic function.

GoodSupportsHIGH confidence
In a multivariable model... glycine was independently and inversely associated with BMI (regression coefficient −0.012; p < .0001). Also, men had significantly lower levels of glycine (regression coefficient −0.061; p = .0026).
William E. Kraus et al. · The Journals of Gerontology Series A · 2016

Why this rating

Consistent inverse association across 6 studies, strong statistical significance.

Source

Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations

William E. Kraus et al. · The Journals of Gerontology Series A · 2016

Meta-analysis · 6 studiesCited 27×
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