Research
Mixed
High adherence to exercise (≥66%) and supplementation (≥80%) allows the intervention to preserve femoral neck bone mineral density and increase total body lean mass, suggesting the protocol is physiologically effective if adhered to.
If you can strictly follow the full exercise and supplement regimen, you may preserve hip bone density and gain lean mass. However, this requires a high level of commitment (n=11 in the study achieved this), which is difficult for most patients.
ModerateQualifiesMEDIUM confidence
Per-protocol analysis of adherent participants (≥66% exercise, ≥80% supplement) showed Ex+Suppl preserved femoral neck aBMD (1.9% [0.1, 3.8], P=0.026) and improved total body lean mass (1.0 kg [-0.23, 2.22], P=0.044) relative to controls.
Why this rating
Per-protocol analysis with a very small subgroup (n=11), limiting statistical power and generalizability.
Source
Musculoskeletal Responses to Exercise Plus Nutrition in Men with Prostate Cancer on Androgen Deprivation: A 12-Month RCT
Jack Dalla Via et al. · Medicine & Science in Sports & Exercise · 2021
DOI 10.1249/mss.0000000000002682
rct · n=70Cited 23×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Mixed
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