Mixed
Caucasian women with obesity exhibit significantly higher in vivo adipose triglyceride (TG) replacement and de novo lipogenesis (DNL) rates compared to African-American women.
This research highlights that the way your body handles fat storage and synthesis (lipid kinetics) may differ based on your race, even if your weight and BMI are similar to others. For Caucasian women with obesity, the study found higher rates of fat turnover and synthesis in fat tissue compared to African-American women. This doesn't mean you can't lose weight, but it suggests that metabolic responses to diet and exercise might vary. It underscores the importance of personalized approaches to health rather than assuming one-size-fits-all metabolic profiles.
We report, for the first time, significant race differences in both TG synthesis and absolute DNL, with Caucasians having higher fTG and fDNL as compared with African-Americans.
Why this rating
The study uses a robust in vivo deuterium labeling protocol (gold standard for measuring lipid kinetics) on a well-defined cohort of 52 women.
Source
Racial differences in in vivo adipose lipid kinetics in humans
Ursula White et al. · Journal of Lipid Research · 2018
DOI 10.1194/jlr.p082628
More from this paper
- Subcutaneous femoral (thigh) adipose tissue has significantly higher triglyceride (TG) replacement rates compared to subcutaneous abdominal (abdominal) adipose tissue in women with obesity.Good
- Higher rates of in vivo adipose triglyceride (TG) synthesis and de novo lipogenesis (DNL) are negatively correlated with body weight loss in women with obesity.Good
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