Research
Energy balance
Modern obesogenic environments (sedentary lifestyle, high-calorie processed food) exploit evolutionary adaptations (brain expansion, efficient fat storage) leading to a 'normalization' of obesity phenotypes and genotypes.
Your environment is shaping your biology. To combat obesity, you must actively create a 'non-obesogenic' environment (healthy food access, physical activity) because your evolutionary biology is wired to store fat in such settings.
LimitedSupportsLOW confidence
These evolutionary mechanisms may inevitably contribute to the emergence of a new niche that, in addition to explaining the obesity pandemic, could ultimately lead to the 'normalization' of phenotypes and genomes associated with obesity.
Why this rating
Theoretical framework based on evolutionary biology, not direct clinical evidence of genomic normalization.
Source
Is obesity the next step in evolution through brain changes?
Wifredo Ricart et al. · Neuroscience Applied · 2023
DOI 10.1016/j.nsa.2023.103927
narrative_reviewCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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