Research
Mixed
Whey protein supplementation (20-40 g/day) combined with resistance training preserves lean body mass and improves strength during GLP-1RA-induced weight loss.
Aim for 1.2-2.0 grams of protein per kilogram of body weight daily. Use whey protein shakes (20-40g) to help meet this goal, especially if you struggle to eat enough solid food. Combine this with resistance training to protect your muscles.
GoodSupportsHIGH confidence
When combined with resistance training, whey protein can help preserve lean body mass during weight loss, with additional strength benefits from creatine monohydrate and β-Hydroxy β-Methylbutyrate supplementation.
Why this rating
Strong mechanistic evidence and data from weight loss populations, though specific GLP-1RA trials are limited.
Source
Dietary supplement considerations during glucagon-like Peptide-1 receptor agonist treatment: A narrative review
Brittany V.B. Johnson et al. · Obesity Pillars · 2025
narrative_reviewCited 4×
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