Energy balance
Isocaloric refeeding after a Very Low Caloric Diet maintains significantly lower fasting plasma glucose levels compared to pre-diet baselines, even after discontinuation of antidiabetic medications, although glucose levels rise from the nadir achieved during the diet.
Even after stopping a strict low-calorie diet and returning to normal eating, people with type 2 diabetes often maintain better blood sugar control than they had before starting the diet. This suggests that a period of intensive dietary intervention can have long-lasting metabolic benefits, even if weight regain occurs.
the mean FPG level after 40 days of refeeding was still markedly lower than that before VLC diet therapy (254 ± 20 vs. 167 ± 14 mg/dl; P < 0.02) despite withdrawal of antidiabetic medication in all subjects.
Why this rating
Same study design as N1, focusing on the refeeding subgroup (n=12).
Source
Glycemic Effects of Intensive Caloric Restriction and Isocaloric Refeeding in Noninsulin-Dependent Diabetes Mellitus*
Robert R. Henry et al. · The Journal of Clinical Endocrinology & Metabolism · 1985
DOI 10.1210/jcem-61-5-917
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