Research
Mixed
IER+MED improves liver function (measured by Alanine Transaminase/ALT) more effectively than a DASH diet, independent of total fat mass loss.
If you have elevated liver enzymes, switching to an IER+MED pattern may offer specific liver health benefits beyond what you get from just eating a healthy diet (DASH).
ModerateSupportsMEDIUM confidence
improvement in alanine transaminase remained significantly greater for IER+MED vs. DASH (−16.2 ± 3.8 U/L vs.–4.0 ± 3.6 U/L, respectively, p = 0.02).
Why this rating
Pilot study, small sample, but statistically significant difference in a specific biomarker.
Source
Effects of Intermittent Energy Restriction Combined with a Mediterranean Diet on Reducing Visceral Adiposity: A Randomized Active Comparator Pilot Study
Chloe Panizza et al. · Nutrients · 2019
DOI 10.3390/nu11061386
rct · n=60Cited 58×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intermittent Energy Restriction combined with a Mediterranean diet (IER+MED) significantly reduces visceral adipose tissue (VAT) and total fat mass more effectively than a continuous euenergetic DASH diet over 12 weeks.Moderate
- While IER+MED reduces visceral adipose tissue (VAT) more than DASH, this advantage disappears when adjusting for total fat mass loss, suggesting the VAT reduction is proportional to overall weight loss rather than specific to visceral fat mobilization.Moderate
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