Research
Mixed
Akkermansia muciniphila supplementation or enrichment improves insulin sensitivity, reduces body weight, and counteracts diet-induced metabolic syndrome in obese or insulin-resistant individuals.
Consider strategies to enrich Akkermansia muciniphila, such as consuming prebiotics like fructooligosaccharides (FOS) or exploring supplementation, to potentially improve insulin sensitivity and manage weight.
GoodSupportsHIGH confidence
Daily oral supplementation with 10^10 A. muciniphila cells was found to improve insulin sensitivity, reduce insulinemia, and decrease body weight over a three-month period.
Why this rating
Supported by human pilot studies and rodent models.
Source
Gut Microbiome: Profound Implications for Diet and Disease
Ronald D. Hills et al. · Nutrients · 2019
DOI 10.3390/nu11071613
narrative_reviewCited 1,109×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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