Research
Energy balance
Targeting surgery on people with severe obesity and impaired glucose tolerance is likely to be more cost-effective, at £2329 per additional life-year.
If you have severe obesity and impaired glucose tolerance, surgery is a highly cost-effective option, costing only £2329 per additional life-year gained.
ModerateSupportsMEDIUM confidence
Targeting surgery on people with severe obesity and impaired glucose tolerance was likely to be more cost-effective, at £2329 per additional life-year.
Why this rating
Based on economic review and modeling, which may have limitations in data quality.
Source
Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement
Alison Avenell et al. · Health Technology Assessment · 2004
DOI 10.3310/hta8210
Meta-analysisCited 1,037×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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