Mixed
Untreated severe OSAS significantly increases long-term cardiovascular morbidity and mortality, whereas compliant CPAP treatment normalizes mortality rates to those of the general population.
If you have severe sleep apnoea, using your CPAP machine consistently every night is the most effective way to protect your heart and prevent early death. The severity of your apnoea matters less than your consistency in using the treatment.
CPAP-treated patients who were compliant with treatment had mortality rates similar to those recorded in the general population, whereas excess cardiovascular fatal events occurred in patients aged <50 yrs who refused CPAP treatment.
Why this rating
Based on longitudinal studies (Marin et al., Doherty et al.) and observational reports, though some studies lack randomization due to ethical constraints.
Source
Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities: Fig. 1—
Walter T. McNicholas et al. · European Respiratory Journal · 2006
DOI 10.1183/09031936.00027406
More from this paper
- Obstructive sleep apnoea syndrome (OSAS) is an independent risk factor for systemic arterial hypertension, with CPAP treatment effectively lowering blood pressure in hypertensive patients.Good
- OSAS is associated with an increased risk of stroke, with severity of sleep-disordered breathing correlating with stroke risk, and CPAP treatment may improve survival in stroke patients with OSAS.Good
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