Mixed
OSAS is associated with an increased risk of stroke, with severity of sleep-disordered breathing correlating with stroke risk, and CPAP treatment may improve survival in stroke patients with OSAS.
If you have sleep apnoea, especially with a high apnoea-hypopnoea index, your risk of stroke is significantly higher. Treating OSAS with CPAP, particularly after a stroke, can improve your long-term survival.
Prospective data from the Wisconsin Sleep Cohort clearly indicate that an AHI >20 was associated with a four-fold increase in the risk of stroke during a 4-yr follow-up study... OSAS could worsen prognosis after a stroke episode, as suggested by the high mortality of patients with an AHI >30 after stroke, and the improvement in 18-month survival of those OSAS patients (AHI <20) who were able to tolerate CPAP treatment after stroke.
Why this rating
Supported by prospective cohort studies (Wisconsin, Caerphilly) and observational data, though some uncertainties remain regarding the exact temporal relationship and independent association with transient ischaemic attacks.
Source
Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities: Fig. 1—
Walter T. McNicholas et al. · European Respiratory Journal · 2006
DOI 10.1183/09031936.00027406
More from this paper
- Obstructive sleep apnoea syndrome (OSAS) is an independent risk factor for systemic arterial hypertension, with CPAP treatment effectively lowering blood pressure in hypertensive patients.Good
- Untreated severe OSAS significantly increases long-term cardiovascular morbidity and mortality, whereas compliant CPAP treatment normalizes mortality rates to those of the general population.Good
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