Research

Micronutrients & recovery

Quercetin aglycone supplementation at doses of 500 mg or higher significantly reduces blood pressure in individuals with stage 1 hypertension, whereas it has no significant effect on normotensive or pre-hypertensive individuals.

If you have Stage 1 hypertension, taking 500 mg or more of quercetin aglycone daily may help lower your blood pressure by a few mmHg. However, if your blood pressure is already normal, this supplement is unlikely to provide cardiovascular benefits. Consult your doctor before starting, especially if you are on medication.

GoodQualifiesHIGH confidence
Edwards et al. [72] found that 730 mg quercetin aglycone was effective in reducing blood pressure in patients diagnosed with stage 1 hypertension, but not in pre-hypertensive individuals... a meta-analysis review evaluated the effectiveness of quercetin supplement in lowering blood pressure in 7 trials. Results showed that a dosage of ≥500 mg quercetin aglycone supplement significantly reduced systolic and diastolic blood pressure...
Wijdan M. Dabeek et al. · Nutrients · 2019

Why this rating

Based on multiple human clinical trials and a meta-analysis, though sample sizes vary and some studies show null results in non-hypertensive groups.

Source

Dietary Quercetin and Kaempferol: Bioavailability and Potential Cardiovascular-Related Bioactivity in Humans

Wijdan M. Dabeek et al. · Nutrients · 2019

narrative_reviewCited 798×
Read the paper

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →