Research
Micronutrients & recovery
Dietary fat co-ingestion significantly enhances the absorption of quercetin aglycone supplements.
Take quercetin aglycone supplements with a meal containing fat to maximize absorption. Studies show high-fat meals can increase plasma quercetin concentration by 45% compared to fat-free meals.
ModerateSupportsMEDIUM confidence
Maximum concentration of total plasma quercetin increased by 12% after the low-fat trial and increased by 45% after high-fat trial (p < 0.05). Enhanced quercetin absorption after the high-fat trial can be explained by increased incorporation into the micelle, soluble fat droplet, indicating that the co-ingestion of quercetin with dietary fat increases absorption from the small intestine.
Why this rating
Based on a single crossover study (Guo et al. [60]) with a small sample size (n=12 implied or similar context).
Source
Dietary Quercetin and Kaempferol: Bioavailability and Potential Cardiovascular-Related Bioactivity in Humans
Wijdan M. Dabeek et al. · Nutrients · 2019
DOI 10.3390/nu11102288
narrative_reviewCited 798×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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