Research

Micronutrients & recovery

Omega-3 fatty acid supplementation does not significantly alter ALT levels in individuals with MASLD.

Taking Omega-3 fatty acid supplements does not significantly lower liver enzymes (ALT) in people with MASLD compared to control groups. While Omega-3s are generally healthy, they should not be relied upon as a primary treatment for improving liver health biomarkers in this condition.

ModerateRefutesMEDIUM confidence
LCHF/ketogenic diets (n = 6) and Omega-3 fatty acids supplementation (n = 4) did not significantly alter ALT.
Ute Stern et al. · European Journal of Nutrition · 2026

Why this rating

Meta-analysis of 4 RCTs, non-significant result.

Source

The impact of dietary interventions on liver health biomarkers in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD): a systematic literature review and meta-analysis of randomized controlled trials

Ute Stern et al. · European Journal of Nutrition · 2026

Meta-analysis · 24 studiesCited 4×
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