Micronutrients & recovery
Omega-3 fatty acid supplementation does not significantly alter ALT levels in individuals with MASLD.
Taking Omega-3 fatty acid supplements does not significantly lower liver enzymes (ALT) in people with MASLD compared to control groups. While Omega-3s are generally healthy, they should not be relied upon as a primary treatment for improving liver health biomarkers in this condition.
LCHF/ketogenic diets (n = 6) and Omega-3 fatty acids supplementation (n = 4) did not significantly alter ALT.
Why this rating
Meta-analysis of 4 RCTs, non-significant result.
Source
The impact of dietary interventions on liver health biomarkers in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD): a systematic literature review and meta-analysis of randomized controlled trials
Ute Stern et al. · European Journal of Nutrition · 2026
DOI 10.1007/s00394-025-03870-z
More from this paper
- Fasting interventions significantly reduce liver health biomarkers (ALT and liver stiffness) in individuals with MASLD compared to control diets.Good
- The Mediterranean Diet (MedDiet) significantly improves liver health biomarkers (ALT, liver stiffness, and MRI-PDFF) in individuals with MASLD.Good
- Low-Carbohydrate High-Fat (LCHF) and Ketogenic diets do not significantly alter ALT levels in individuals with MASLD compared to control diets.Moderate
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