Research

Micronutrients & recovery

Vitamin D3 supplementation significantly reduces cancer-specific mortality.

Vitamin D3 may help reduce the risk of dying from cancer. This finding is based on a smaller subset of trials than the general mortality benefit, so it should be viewed as a potential secondary benefit rather than the primary reason for supplementation. The reduction is statistically significant but modest.

ModerateSupportsMEDIUM confidence
Vitamin D3 statistically significantly decreased cancer mortality (RR 0.88 (95% CI 0.78 to 0.98); P = 0.02; I2 = 0%; 44,492 participants; 4 trials).
Goran Bjelaković et al. · Cochrane Database of Systematic Reviews · 2014

Why this rating

Statistically significant but based on only 4 trials and 44,492 participants; trial sequential analysis did not cross the monitoring boundary for benefit.

Source

Vitamin D supplementation for prevention of mortality in adults

Goran Bjelaković et al. · Cochrane Database of Systematic Reviews · 2014

Meta-analysis · 56 studiesCited 677×
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