Hormonal
Specific fatty acid profiles and the physico-chemical structure of dietary fats (e.g., emulsification) differentially influence postprandial endotoxemia and inflammation, with some unsaturated fats potentially causing higher endotoxemia than saturated fats.
Don't assume vegetable oils are always better for gut inflammation than butter. The physical state of the fat (emulsified vs. solid) and the specific fatty acid profile matter. Emulsified oils may increase LPS absorption more than solid fats. Consider combining high-fat meals with anti-inflammatory foods like orange juice to mitigate these effects.
Postprandial endotoxaemia was also higher in the group fed emulsified sunflower oil... showing that the physico-chemical structure of fat can affect the levels of circulating LPS as well.
Why this rating
Based on specific animal and human studies cited in the review.
Source
Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia
Ana Paula Boroni Moreira et al. · British Journal Of Nutrition · 2012
DOI 10.1017/s0007114512001213
More from this paper
- High-fat diets increase circulating lipopolysaccharide (LPS) levels (metabolic endotoxemia) through chylomicron-mediated absorption and increased intestinal permeability, leading to subclinical inflammation and insulin resistance.Good
- Prebiotics and probiotics can reduce metabolic endotoxemia and intestinal permeability by modulating gut microbiota composition and improving gut barrier function.Good
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