Research

Micronutrients & recovery

L-carnitine supplementation ameliorates complications in uremic patients undergoing hemodialysis, including cardiac dysfunction, intradialytic hypotension, and erythropoietin-resistant anemia.

If you are on hemodialysis, your body likely loses carnitine during treatment, which can worsen heart function, cause low blood pressure during sessions, and make anemia harder to treat. Discussing L-carnitine supplementation with your nephrologist may help manage these specific complications, although you should be aware that clinical evidence is still evolving.

ModerateSupportsMEDIUM confidence
L-Carnitine supplementation can lead to improvements in several complications seen in uremic patients, including cardiac complications, impaired exercise and functional capacities, muscle symptoms, increased symptomatic intradialytic hypotension, and erythropoietin-resistant anemia through normalizing the reduced carnitine palmitoyl transferase activity in red cells [43].
Judith Flanagan et al. · Nutrition & Metabolism · 2010

Why this rating

The paper cites improvements but also notes Hanadelman's caution that evidence suffers from limited subject numbers and open-label designs.

Source

Role of carnitine in disease

Judith Flanagan et al. · Nutrition & Metabolism · 2010

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