Research
Mixed
Roux-en-Y gastric bypass (RYGB) surgery provides superior long-term weight loss maintenance and significantly higher rates of diabetes remission compared to non-surgical controls in severely obese patients over a 6-year period.
For severely obese individuals (BMI >= 35) who have not achieved lasting weight loss through lifestyle changes, Roux-en-Y gastric bypass surgery offers a clinically proven path to significant, long-term weight loss (average 27.7% at 6 years) and high rates of type 2 diabetes remission (62%), far exceeding the outcomes of non-surgical management.
GoodSupportsHIGH confidence
Six years after surgery, patients who received RYGB surgery (with 92.6% follow-up) lost 27.7% (95% CI, 26.6%-28.9%) of their initial body weight compared with 0.2% (95% CI, −1.1% to 1.4%) gain in control group 1... Diabetes remission rates 6 years after surgery were 62% (95% CI, 49%-75%) in the RYGB surgery group, 8% (95% CI, 0%-16%) in control group 1... The incidence of diabetes throughout the course of the study was reduced after RYGB surgery (2%; 95% CI, 0%-4%; vs 17%; 95% CI, 10%-24%)
Why this rating
Prospective study with large sample size (n=1156), long follow-up (6 years), and propensity score adjustment, though not a randomized controlled trial.
Source
Health Benefits of Gastric Bypass Surgery After 6 Years
Ted D. Adams et al. · JAMA · 2012
cohort · n=1156Cited 669×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →