Research

Energy balance

Panax ginseng berry extract reduces body weight in obese mice by decreasing food intake and increasing energy expenditure, whereas its isolated active component, ginsenoside Re, lowers blood glucose without affecting body weight.

The full Panax ginseng berry extract helps obese mice lose weight by making them eat less and burn more energy. However, the specific compound responsible for lowering blood sugar (ginsenoside Re) does not cause weight loss. This suggests that if you are looking for blood sugar control, you might not need the weight-loss effects, and if you want weight loss, you need the full extract, not just the isolated glucose-lowering component.

ModerateQualifiesMEDIUM confidence
After a 12-day treatment with extract at 150 mg/kg, body weight reduced significantly... There was a significant difference in daily food intake... Energy expenditure values... significant increase in energy expenditure... In contrast to both the antidiabetic and anti-obese effects of Panax ginseng berry extract, after a 12-day treatment with 20 mg/kg ginsenoside Re, body weight did not change significantly.
Anoja S. Attele et al. · Diabetes · 2002

Why this rating

Animal study with clear mechanistic data on energy expenditure and food intake.

Source

Antidiabetic Effects of <i>Panax ginseng</i> Berry Extract and the Identification of an Effective Component

Anoja S. Attele et al. · Diabetes · 2002

DOI 10.2337/diabetes.51.6.1851

mechanism_onlyCited 547×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →