Energy balance
Panax ginseng berry extract reduces body weight in obese mice by decreasing food intake and increasing energy expenditure, whereas its isolated active component, ginsenoside Re, lowers blood glucose without affecting body weight.
The full Panax ginseng berry extract helps obese mice lose weight by making them eat less and burn more energy. However, the specific compound responsible for lowering blood sugar (ginsenoside Re) does not cause weight loss. This suggests that if you are looking for blood sugar control, you might not need the weight-loss effects, and if you want weight loss, you need the full extract, not just the isolated glucose-lowering component.
After a 12-day treatment with extract at 150 mg/kg, body weight reduced significantly... There was a significant difference in daily food intake... Energy expenditure values... significant increase in energy expenditure... In contrast to both the antidiabetic and anti-obese effects of Panax ginseng berry extract, after a 12-day treatment with 20 mg/kg ginsenoside Re, body weight did not change significantly.
Why this rating
Animal study with clear mechanistic data on energy expenditure and food intake.
Source
Antidiabetic Effects of <i>Panax ginseng</i> Berry Extract and the Identification of an Effective Component
Anoja S. Attele et al. · Diabetes · 2002
DOI 10.2337/diabetes.51.6.1851
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →