Hormonal
Mandatory quarantine and social isolation induce chronic stress, anxiety, and depression, which physiologically increase sympathetic nervous activity and catecholamines, thereby accelerating atherosclerosis and increasing cardiovascular disease risk.
Understand that the stress of quarantine is not just 'in your head' but has real physical effects on your heart. To mitigate this, actively manage stress through relaxation techniques, maintain social connections virtually, and prioritize sleep to counteract the sympathetic nervous system activation caused by isolation.
In the case of quarantine people suffered from a chronic increase of sympathetic nervous activity leading to a chronic negative effect on heart and vessels... Stress-related changes in the sympatheticeparasympathetic balance and the neuroendocrine dysregulation involving the hypothal- amusepituitarye adrenal responses might adversely affect the cardiovascular system both by accelerating the atherosclerotic process and by precipitating the occurrence of a cardiovascular event.
Why this rating
The paper is a viewpoint/commentary citing observational data and physiological mechanisms, not a randomized controlled trial.
Source
Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease
Anna Vittoria Mattioli et al. · Nutrition Metabolism and Cardiovascular Diseases · 2020
DOI 10.1016/j.numecd.2020.05.020
More from this paper
- Quarantine leads to unhealthy dietary habits, specifically increased consumption of energy-dense, shelf-stable foods (high in sugar, salt, and trans-fats) and decreased intake of fresh fruits and vegetables, resulting in micronutrient deficiency and increased oxidative stress.Moderate
- Quarantine leads to reduced physical activity and increased sedentary behavior, which rapidly reverses beneficial metabolic and cardiovascular adaptations, leading to insulin resistance, increased blood pressure, and higher cardiovascular risk.Moderate
- Vitamin D supplementation may reduce the severity and risk of COVID-19 infection, particularly in individuals with vitamin D deficiency, by modulating immune response and reducing pro-inflammatory cytokines.Limited
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