Energy balance
Caloric restriction (20-40% reduction) and regular physical training delay mitochondrial aging and attenuate age-related dysfunction in humans by enhancing mitochondrial biogenesis and reducing oxidative stress.
To support your mitochondria and slow aging, aim to eat 20-40% fewer calories than your maintenance needs while maintaining a regular exercise routine. This combination has been shown to significantly reduce cardiovascular risk and improve mitochondrial efficiency. Focus on nutrient-dense foods to manage hunger and consistency in physical activity to maximize benefits.
implementation of strategies such as caloric restriction and regular physical training may delay mitochondrial aging and attenuate the age-related phenotype in humans.
Why this rating
Supported by the CALERIE trial (human data) and extensive animal model data, though the paper is a review.
Source
Mitochondrial Aging and Age-Related Dysfunction of Mitochondria
Dimitry A. Chistiakov et al. · BioMed Research International · 2014
DOI 10.1155/2014/238463
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