Research
Micronutrients & recovery
Supplementation with glycine and cysteine increases glutathione (GSH) concentration and biosynthesis rates, leading to a significant decrease in oxidative stress biomarkers in the blood plasma of elderly persons.
Supplementing with glycine and cysteine can boost glutathione levels and reduce oxidative stress in older adults. This suggests that targeted amino acid supplementation may be a useful strategy for supporting antioxidant defenses in aging.
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However, glycine and cysteine supplementation led to an increase in GSH concentration and rate of its biosynthesis along with a significant decrease in levels of oxidative stress biomarkers in the blood plasma.
Why this rating
Based on measurements in younger and elderly persons, reviewed in the paper.
Source
Oxidative Stress and Advanced Lipoxidation and Glycation End Products (ALEs and AGEs) in Aging and Age-Related Diseases
Nurbubu T. Moldogazieva et al. · Oxidative Medicine and Cellular Longevity · 2019
DOI 10.1155/2019/3085756
narrative_reviewCited 493×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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