Research
Micronutrients & recovery
The Mediterranean diet, characterized by high intake of polyphenols, fiber, and omega-3 fatty acids, counteracts oxidative stress and insulin resistance in Type 2 Diabetes by activating the NRF2 antioxidant pathway and reducing pro-inflammatory eicosanoids.
Adopt a Mediterranean-style eating pattern focusing on vegetables, fruits, whole grains, legumes, nuts, and extra virgin olive oil. Limit meat and processed foods. This approach helps manage oxidative stress and insulin resistance through natural antioxidants and anti-inflammatory fats.
ModerateSupportsMEDIUM confidence
The MD’s efficacy against oxidative stress is attributed to the presence of natural antioxidants found primarily in vegetables, fruits, and spices. These foods contain phytochemicals such as polyphenols, phytosterols, and carotenoids, which activate the nuclear factor erythroid 2-related factor 2 (NRF2)... Oleic and linoleic acids have anti-inflammatory effects by reducing pro-inflammatory eicosanoids derived from arachidonic acid and increasing the production of anti-inflammatory eicosanoids [72].
Why this rating
The paper is a narrative review summarizing multiple studies; it does not present new primary clinical trial data.
Source
Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications
Alfredo Caturano et al. · Current Issues in Molecular Biology · 2023
narrative_reviewCited 490×
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