Mixed
While HP-HMB supplementation significantly reduces mortality and improves nutritional status (SGA class) and body weight at 30 days, it does not significantly reduce the rate of nonelective hospital readmission in malnourished older adults.
If you are an older adult hospitalized for heart or lung issues and are malnourished, using a high-protein HMB supplement will likely help you gain weight and improve your nutritional status, and it may save your life. However, you should not expect it to prevent hospital readmissions on its own.
There was no significant difference between groups for the primary composite endpoint... No significant differences were observed between groups for the 90-day readmission rate.
Why this rating
Robust RCT design, clear negative finding for readmission.
Source
Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial
Nicolaas E.P. Deutz et al. · Clinical Nutrition · 2016
DOI 10.1016/j.clnu.2015.12.010
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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