Research
Micronutrients & recovery
Supplementation with Vitamin E and Ascorbic Acid (Vitamin C) does not significantly reduce the risk of coronary heart disease, and may have adverse effects in some trials.
Do not rely on Vitamin E or Vitamin C supplements to prevent heart disease, as evidence shows they are not significantly associated with reduced risk and may have adverse effects in some trials.
GoodRefutesHIGH confidence
Insufficient evidence... of association is present for intake of supplementary vitamin E and ascorbic acid (vitamin C)... results of some RCTs of dietary supplements paradoxically revealed adverse effects on CHD for certain nutrients
Why this rating
Strong evidence from RCTs showing no benefit or potential harm, despite observational data suggesting benefits from food sources.
Source
A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors and Coronary Heart Disease
Andrew Mente et al. · Archives of Internal Medicine · 2009
Meta-analysis · 189 studiesCited 1,280×
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