Energy balance
Impaired fat oxidation capacity in skeletal muscle contributes to intramyocellular lipid accumulation and insulin resistance.
Your muscles' ability to burn fat is crucial for metabolic health. If you can't oxidize fat efficiently, it builds up in your muscles, contributing to insulin resistance. Improving physical fitness and aerobic capacity can enhance fat oxidation and reduce intramuscular lipid stores.
whole body fat oxidation is impaired, leading to ectopic accumulation of intracellular lipid. This view holds that the machinery to oxidize fat is not sufficient to match the dietary fat load or is not activated in a timely fashion...
Why this rating
Supported by animal models showing correlation between inhibited fat oxidation and insulin resistance, and human studies linking low fat oxidation to weight gain and insulin sensitivity.
Source
Increased Fat Intake, Impaired Fat Oxidation, and Failure of Fat Cell Proliferation Result in Ectopic Fat Storage, Insulin Resistance, and Type 2 Diabetes Mellitus
Éric Ravussin et al. · Annals of the New York Academy of Sciences · 2002
DOI 10.1111/j.1749-6632.2002.tb04292.x
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