Research
Energy balance
RYGB surgery leads to decreased faecal bile acids and altered energy metabolism, including decreased urinary succinate, 2-oxoglutarate, citrate, and fumarate, indicating modulated mitochondrial function.
Surgery changes how the body processes energy, reducing certain metabolic byproducts in urine. This suggests a shift in how mitochondria function after surgery.
ModerateSupportsMEDIUM confidence
Faecal extraction studies reveal a decrease in faecal bile acids... We find decreased urinary amines and cresols and demonstrate indices of modulated energy metabolism post-RYGB including decreased urinary succinate, 2-oxoglutarate, citrate and fumarate.
Why this rating
Based on rat model data; human relevance is inferred but not directly measured in this specific study's primary outcomes.
Source
Metabolic surgery profoundly influences gut microbial–host metabolic cross-talk
Jia V. Li et al. · Gut · 2011
DOI 10.1136/gut.2010.234708
mechanism_only · n=29Cited 446×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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