Research

Micronutrients & recovery

Higher blood 25-hydroxyvitamin D concentrations are associated with a reduced risk of colorectal cancer, but this protective association is not observed for breast or prostate cancer.

Maintaining adequate Vitamin D levels may help lower the risk of colorectal cancer, as higher blood levels are linked to a modest reduction in risk. However, this benefit does not extend to breast or prostate cancer based on current observational data. Focus on overall health rather than expecting Vitamin D to prevent all cancers.

ModerateQualifiesMEDIUM confidence
Mixed-effects dose-response meta-analyses showed that each 10-nmol/L increase in blood 25-(OH)D concentration was associated with a 6% (95% CI, 3% to 9%) reduced risk for colorectal cancer but no statistically significant dose-response relationships for prostate and breast cancer.
Mei Chung et al. · Annals of Internal Medicine · 2011

Why this rating

Based on observational studies (nested case-control) which are subject to confounding, though the dose-response analysis is robust for colorectal cancer.

Source

Vitamin D With or Without Calcium Supplementation for Prevention of Cancer and Fractures: An Updated Meta-analysis for the U.S. Preventive Services Task Force

Mei Chung et al. · Annals of Internal Medicine · 2011

Meta-analysis · 47 studiesCited 415×
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