Research
Hormonal
High consumption of soy and isoflavones is associated with a decreased risk of post-menopausal breast cancer and localized prostate cancer.
If you consume soy products like tofu, miso, or natto regularly, current evidence from large Japanese cohorts suggests this dietary pattern is associated with a lower risk of breast and prostate cancer. This is likely due to the hormonal modulation properties of isoflavones.
GoodSupportsHIGH confidence
In the JPHC Study, we found an inverse association between dietary isoflavones and post-menopausal breast cancer (2) and localized prostate cancer (3).
Why this rating
Large prospective cohort (JPHC) with nested case-control studies, though observational nature limits causal inference.
Source
The JPHC Study: Design and Some Findings on the Typical Japanese Diet
Shoichiro Tsugane et al. · Japanese Journal of Clinical Oncology · 2014
DOI 10.1093/jjco/hyu096
cohort · n=140420Cited 384×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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