Research
Macro partitioning
High intake of fish and n-3 fatty acids is associated with a decreased risk of proximal colon cancer, liver cancer, and myocardial infarction.
Eating fish regularly, as is common in Japanese diets, is associated with a lower risk of heart attacks and certain cancers (colon, liver). This dietary pattern appears safe and beneficial.
GoodSupportsHIGH confidence
In the JPHC Study, we found an inverse association between fish and n-3 fatty acid and cancers of the proximal colon (13) and liver (14), myocardial infarction (15)... No evidence of any harmful health effect of fish and n-3 fatty acids has been obtained to date.
Why this rating
Large prospective cohort with consistent inverse associations across multiple disease endpoints.
Source
The JPHC Study: Design and Some Findings on the Typical Japanese Diet
Shoichiro Tsugane et al. · Japanese Journal of Clinical Oncology · 2014
DOI 10.1093/jjco/hyu096
cohort · n=140420Cited 384×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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